- Szczesny B, Boorgula MP, Chavan S, Campbell M, Johnson RK, Kammers K, Thompson EE, Cox MS, Shankar G, Cox C, Morin A, Lorizio W, Daya M, Kelada SNP, Beaty TH, Doumatey AP, Cruz AA, Watson H, Naureckas ET, Giles BL, Arinola GA, Sogaolu O, Falade AG, Hansel NN, Yang IV, Olopade CO, Rotimi CN, Landis RC, Figueiredo CA, Altman MC, Kenny E, Ruczinski I, Liu AH, Ober C, Taub MA, Barnes KC, Mathias RA. Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations. Nature Communications 15: 4546, 2024.
- Donoghue LJ, Markovetz MR, Morrison CB, Chen G, McFadden KM, Sadritabrizi T, Gutay MI, Kato T, Rogers TD, Snead JY, Livraghi-Butrico A, Button B, Ehre C, Grubb BR, Hill DB, Kelada SNP. BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance. American Journal Physiology-Lung Cellular and Molecular Physiology 325: L765–L775, 2023.
- Donoghue LJ, McFadden KM, Vargas D, Smith GJ, Immormino RM, Moran TP, Kelada SNP. Collaborative Cross Strain CC011/UncJ as a novel mouse model of T2-high, severe asthma. Respiratory Research 2023;24(1):153.
- Van Buren E, Radicioni G, Lester S, O’Neal WK, Dang H, Kasela S, Garudadri S, Curtis JL, Han ML, Krishnan JA, Wan ES, Silverman EK, Hastie A, Ortega VE, Lappalainen T, Christenson SA, Li Y, Cho MH, Kesimer M, Kelada SNP. Genetic Regulators of Sputum Mucin Concentration and Their Associations with COPD Phenotypes. PLoS Genetics 2023;19(6):e1010445.
- Virk R, Buddenbaum N, Al-Shaer A, Armstrong M, Manke J, Reisdorph N, Sergin S, Fenton JI, Wallace ED, Ehrmann BM, Lovins HB, Gowdy KM, Smith MR, Smith GJ, Kelada SNP, Shaikh SR. Obesity reprograms the pulmonary polyunsaturated fatty acid-derived lipidome, transcriptome, and gene-oxylipin networks. J Lipid Res. 2022;63: 100267.
- Tovar A, Smith GJ, Nalesnik MB, Thomas JM, McFadden KM, Harkema JR, Kelada SNP. A Locus on Chromosome 15 Contributes to Acute Ozone-Induced Lung Injury in Collaborative Cross Mice. Am J Respir Cell Mol Biol 2022; doi:10.1165/RCMB.2021-0326OC.
- Rogers TD, Button B, Kelada SNP, Ostrowski LE, Livraghi-Butrico A, Gutay MI, Esther CR Jr, Grubb BR. Regional Differences in Mucociliary Clearance in the Upper and Lower Airways. Front Physiol. 2022;13. doi:10.3389/FPHYS.2022.842592
- Tovar A.*, Crouse W.L.*, Smith G.J., Thomas J.M., Keith B.P., McFadden K.M., Morgan T.P., Furey T.S.#, Kelada S.N.P.# Integrative phenotypic and genomic analyses reveal strain-dependent responses to acute ozone exposure and their associations with airway macrophage transcriptional activity. The American Journal of Physiology-Lung Cellular and Molecular Physiology, 322(1):L33-L49.
- Smith GJ, Tovar A, Kanke M, Wang Y, Deshane JS, Sethupathy P, Kelada SNP. Ozone-induced changes in the murine lung extracellular vesicle small RNA landscape. Physiol Rep. 2021 Sep;9(18):e15054.
- Kong X, Bennett WC, Jania CM, Chason KD, German Z, Adouli J, Budney SD, Oby BT, van Heusden C, Lazarowski ER, Jaspers I, Randell SH, Hedgespeth BA, Cruse G, Hua X, Schworer SA, Smith GJ, Kelada SNP, Tilley SL. Identification of an ATP-P2X7-mast cell pathway mediating ozone-induced bronchial hyperresponsiveness. JCI Insight. 2021 Sep 21:e140207.
- Crouse WL, Kelada SNP, Valdar W. Inferring the Allelic Series at QTL in Multiparental Populations. Genetics 2020; 216: 957-983.
- Laudermilk LT, Tovar A, Homstad AK, Thomas JM, Mcfadden KM, Tune MK, Cowley DO, Mock JR, Ideraabdullah F, Kelada SNP. Baseline and innate immune response characterization of a Zfp30 knockout mouse strain. Mammalian Genome 2020; 31: 205–213.
- Tovar A, Smith G, Thomas J, Harkema JR, Kelada SNP. Transcriptional profiling of the murine airway response to acute ozone exposure. Toxicological Sciences 2019; 173(1): 114-130.
- Keele G, Crouse W, Kelada SNP, Valdar W. Determinants of QTL mapping power in the realized Collaborative Cross. Genes|Genomes|Genetics 2019;9:1707-1723.
- Smith GS, Walsh W, Higuchi M, Kelada SNP. Development of a large-scale computer-controlled ozone inhalation exposure system for rodents. Inhalation Toxicology 2019;31(2):61-72. pdf
- Tsai Y, Parker JS, Yang IV, Kelada SNP. Meta-analysis of Airway Epithelia Gene Expression in Asthma. European Respiratory Journal 2018;51(5):1701962. pdf
- Laudermilk LT, Thomas JM, Kelada SNP. Differential Regulation of Zfp30 Expression in Murine Airway Epithelia Through Altered Binding of ZFP148 to rs51434084. G3: Genes | Genomes | Genetics 2018;8(2):687-693. pdf
- Donoghue LJ*, Livraghi-Butrico A*, McFadden KM, Thomas JM, Chen G, Grubb BR, O’Neal WK, Boucher RC, Kelada SNP. Identification of trans protein QTL for secreted airway mucins in mice and a causal role for Bpifb1. Genetics 2017;207:801-812. pdf
- Kelada SNP. Plethysmography Phenotype QTL in Mice Before and After Allergen Sensitization and Challenge. G3: Genes | Genomes | Genetics 2016; 6(9):2857-2865. pdf
- Rutledge H, Baran-Gale J, Pardo-Manuel de Villena F, Chesler EJ, Churchill GA, Sethupathy P*, Kelada SNP*. Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population. BMC Genomics 2015; 16:633. pdf
- Rutledge H, Aylor DL, Carpenter DE, Peck BCE, Chines P, Ostrowski LE, Chessler EJ, Churchill GA, Pardo-Manuel de Villena F, Kelada SN. Genetic Regulation of Zfp30, CXCL1, and Neutrophilic in Mouse Lung. Genetics 2014;198(2):735-45. pdf
- Collins AL, Kim Y, Bloom RJ, Kelada SN, Sethupathy P, Sullivan PF. Transcriptional targets of the schizophrenia risk gene miR-137. Translational Psychiatry 2014;4:e404. pdf
- Kelada SN, Carpenter DE, Aylor DL, Chines P, Rutledge H, Chessler EJ, Churchill GA, Pardo-Manuel de Villena F, Schwartz DA, Collins FS. Integrative Genetic Analysis of Allergic Inflammation in the Murine Lung. The American Journal of Respiratory Cellular Molecular Biology 2014; 51(3): 436-445. pdf Red Journal Research Highlight
- Kelada SN*, Sethupathy P*, Okoye IS*, Kistasis E, Czieso S, White S.D., Chou D, Martens C, Ricklefs SM, Virtaneva K, Sturdevant DE, Porcella SF, Belkaid Y, Wynn TA, Wilson MS. miR-182 and miR-10a are key regulators of Treg function during Th2 and Th1-associated inflammation. PLoS Pathogens 2013; 9(6):e1003451. pdf
- Kelada SN*, Aylor DA*, Peck B, Ryan JF, Miller D, Chesler E, Threadgill DW, Pardo-Manuel de Villena F, Churchill GA, Collins FS. Genetic Analysis of Hematological Parameters in Incipient Lines of the Collaborative Cross Mice. G3: Genes | Genomes | Genetics 2012; 2(2): 157-165. pdf
- Collaborative Cross Consortium. The Genome Architecture of the Collaborative Cross Mouse Genetic Reference Population. Genetics 2012; 190(2): 389-401. pdf
- Kelada SN, Wilson MS, Tavarez U, Borate B, Whitehead GS, Maruoka S, Roy MG, Olive M, Carpenter DE, Brass DM, Wynn TA, Cook DN, Evans CM, Schwartz DA, Collins FS. Strain-Dependent Genomic Factors Affect Allergen-Induced Airway Hyper-responsiveness in Mice. The American Journal of Respiratory Cellular Molecular Biology 2011; 45(4):817-24. pdf
- Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo R, Baric RS, Ferris M, Frelinger JA, Heise M, Frieman M, Gralinski L, Bell T, Didion JD, Hua K, Nehrenberg D, Powell C, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu E, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi F, Pomp D, Threadgill DW, Pardo-Manuel de Villena F, Churchill GA. Genetic Analysis of Complex Traits in the Emerging Collaborative Cross. Genome Research 2011; 21(8): 1213-22. pdf
* co-first author
For a full list of publications by Samir Kelada, see his Curriculum Vitae.