PUBLICATIONS

  1. Tovar A, Smith GJ, Nalesnik MB, Thomas JM, McFadden KM, Harkema JR, Kelada SNP. A Locus on Chromosome 15 Contributes to Acute Ozone-Induced Lung Injury in Collaborative Cross Mice. Am J Respir Cell Mol Biol 2022;doi:10.1165/RCMB.2021-0326OC.
  2. Rogers TD, Button B, Kelada SNP, Ostrowski LE, Livraghi-Butrico A, Gutay MI, Esther CR Jr, Grubb BR. Regional Differences in Mucociliary Clearance in the Upper and Lower Airways. Front Physiol. 2022;13. doi:10.3389/FPHYS.2022.842592
  3. Tovar A.*, Crouse W.L.*, Smith G.J., Thomas J.M., Keith B.P., McFadden K.M., Morgan T.P., Furey T.S.#, Kelada S.N.P.# Integrative phenotypic and genomic analyses reveal strain-dependent responses to acute ozone exposure and their associations with airway macrophage transcriptional activity. The American Journal of Physiology-Lung Cellular and Molecular Physiology, 322(1):L33-L49.
  4. Smith GJ, Tovar A, Kanke M, Wang Y, Deshane JS, Sethupathy P, Kelada SNP. Ozone-induced changes in the murine lung extracellular vesicle small RNA landscape. Physiol Rep. 2021 Sep;9(18):e15054.
  5. Kong X, Bennett WC, Jania CM, Chason KD, German Z, Adouli J, Budney SD, Oby BT, van Heusden C, Lazarowski ER, Jaspers I, Randell SH, Hedgespeth BA, Cruse G, Hua X, Schworer SA, Smith GJ, Kelada SNP, Tilley SL. Identification of an ATP-P2X7-mast cell pathway mediating ozone-induced bronchial hyperresponsiveness. JCI Insight. 2021 Sep 21:e140207.
  6. Crouse WL, Kelada SNP, Valdar W. Inferring the Allelic Series at QTL in Multiparental Populations. Genetics 2020; 216: 957-983.
  7. Laudermilk LT, Tovar A, Homstad AK, Thomas JM, Mcfadden KM, Tune MK, Cowley DO, Mock JR, Ideraabdullah F, Kelada SNP. Baseline and innate immune response characterization of a Zfp30 knockout mouse strain. Mammalian Genome 2020; 31: 205–213.
  8. Tovar A, Smith G, Thomas J, Harkema JR, Kelada SNP. Transcriptional profiling of the murine airway response to acute ozone exposure. Toxicological Sciences 2019; 173(1): 114-130.
  9. Keele G, Crouse W, Kelada SNP, Valdar W. Determinants of QTL mapping power in the realized Collaborative Cross. Genes|Genomes|Genetics 2019;9:1707-1723. pdf
  10. Smith GS, Walsh W, Higuchi M, Kelada SNP. Development of a large-scale computer-controlled ozone inhalation exposure system for rodents. Inhalation Toxicology 2019;31(2):61-72. pdf
  11. Tsai Y, Parker JS, Yang IV, Kelada SNP. Meta-analysis of Airway Epithelia Gene Expression in Asthma. European Respiratory Journal 2018. pdf
  12. Laudermilk LT, Thomas JM, Kelada SNP. Differential Regulation of Zfp30 Expression in Murine Airway Epithelia Through Altered Binding of ZFP148 to rs51434084. G3: Genes | Genomes | Genetics 2018;8(2):687-693. pdf
  13. Donoghue LJ*, Livraghi-Butrico A*, McFadden KM, Thomas JM, Chen G, Grubb BR, O’Neal WK, Boucher RC, Kelada SNP. ­­Identification of trans protein QTL for secreted airway mucins in mice and a causal role for Bpifb1. Genetics 2017;207:801-812. pdf
  14. Kelada SNP. Plethysmography Phenotype QTL in Mice Before and After Allergen Sensitization and Challenge. G3: Genes | Genomes | Genetics 2016; 6(9):2857-2865. pdf
  15. Rutledge H, Baran-Gale J, Pardo-Manuel de Villena F, Chesler EJ, Churchill GA, Sethupathy P*, Kelada SNP*. Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population. BMC Genomics 2015; 16:633. pdf
  16. Rutledge H, Aylor DL, Carpenter DE, Peck BCE, Chines P, Ostrowski LE, Chessler EJ, Churchill GA, Pardo-Manuel de Villena F, Kelada SN. Genetic Regulation of Zfp30, CXCL1, and Neutrophilic in Mouse Lung. Genetics 2014;198(2):735-45. pdf
  17. Collins AL, Kim Y, Bloom RJ, Kelada SN, Sethupathy P, Sullivan PF. Transcriptional targets of the schizophrenia risk gene miR-137. Translational Psychiatry 2014;4:e404. pdf
  18. Kelada SN, Carpenter DE, Aylor DL, Chines P, Rutledge H, Chessler EJ, Churchill GA, Pardo-Manuel de Villena F, Schwartz DA, Collins FS. Integrative Genetic Analysis of Allergic Inflammation in the Murine Lung. The American Journal of Respiratory Cellular Molecular Biology 2014; 51(3): 436-445. pdf Red Journal Research Highlight
  19. Kelada SN*, Sethupathy P*, Okoye IS*, Kistasis E, Czieso S, White S.D., Chou D, Martens C, Ricklefs SM, Virtaneva K, Sturdevant DE, Porcella SF, Belkaid Y, Wynn TA, Wilson MS. miR-182 and miR-10a are key regulators of Treg function during Th2 and Th1-associated inflammation. PLoS Pathogens 2013; 9(6):e1003451. pdf
  20. Kelada SN*, Aylor DA*, Peck B, Ryan JF, Miller D, Chesler E, Threadgill DW, Pardo-Manuel de Villena F, Churchill GA, Collins FS. Genetic Analysis of Hematological Parameters in Incipient Lines of the Collaborative Cross Mice. G3: Genes | Genomes | Genetics 2012; 2(2): 157-165. pdf
  21. Collaborative Cross Consortium. The Genome Architecture of the Collaborative Cross Mouse Genetic Reference Population. Genetics 2012; 190(2): 389-401. pdf
  22. Bobb JF, Scharfstein DO, Daniels MJ, Collins FS, Kelada SN. Multiple Imputation of Missing Phenotype Data forQTL Mapping.  Statistical Applications in Genetics and Molecular Biology 2011; 10(1): Article 29. pdf
  23. Kelada SN, Wilson MS, Tavarez U, Borate B, Whitehead GS, Maruoka S, Roy MG, Olive M, Carpenter DE, Brass DM, Wynn TA, Cook DN, Evans CM, Schwartz DA, Collins FS. Strain-Dependent Genomic Factors Affect Allergen-Induced Airway Hyper-responsiveness in Mice. The American Journal of Respiratory Cellular Molecular Biology 2011; 45(4):817-24. pdf
  24. Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo R, Baric RS, Ferris M, Frelinger JA, Heise M, Frieman M, Gralinski L, Bell T, Didion JD, Hua K, Nehrenberg D, Powell C, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu E, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi F, Pomp D, Threadgill DW, Pardo-Manuel de Villena F, Churchill GA. Genetic Analysis of Complex Traits in the Emerging Collaborative Cross. Genome Research 2011; 21(8): 1213-22. pdf

* co-first author

For a full list of publications by Samir Kelada, see his Curriculum Vitae.